2023・2022・2021・2020・～2019
2023年度
(59) Mohammad Nuruzzaman, Brandon M. Colella, Chiamaka P. Uzoewulu, Alissa E. Meo, Elizabeth J. Gross, Seiya Ishizawa, Sravani Sana, He Zhang, Meredith E. Hoff, Bryce T. W. Medlock … Hexafluoroisopropanol as a Bioconjugation Medium of Ultrafast, Tryptophan-Selective Catalysis. Journal of the American Chemical Society(2024)
(58) Yugo Mishima, Shusuke Tomoshige, Shinichi Sato, Minoru Ishikawa. Allosteric Hsp70 Modulator YM-1 Induces Degradation of BRD4. Chemical and Pharmaceutical Bulletin 72(2),161-165(2024)
(57) Eugene Futai, Hajime Kawasaki, Shinichi Sato, Khadija Daoudi, Masafumi Hidaka, Taisuke Tomita, Tomohisa Ogawa. A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site. Toxins 15(8), 500-500 (2023)
(56) Nakane K., Hoshino Y., Dodo K., Tomoshige S., Ishikawa M., Furuyama T.*, Sato S.* Near-Infraed-Light-Activatable Proximity Labeling of Beads-Binding Proteins. ChemRxiv doi:10.26434/chemrxiv-2023-443cj
2022年度
(55) Okamoto Y.*, Mabuchi T., Nakane K., Ueno A., Sato S.* Switching Type I/Type II Reactions by Turning a Photoredox Catalyst into a Photo-Driven Artificial Metalloenzyme, ACS, Catal. 13, 4131–4141 (2023) (supplementary cover、東北大プレスリリース）
(54) Yamano T., Onizuka K.*, Sasaki M., Sato S., Natatsugi F.* Photocahemical Labeling of Nucleic Acid by Photocatalyst Tethered DNA Probe. Chem. Lett. 51, 1121–1124 (2022).
(53) Nakane K., Nagasawa H., Fujimura C., Koyanagi E., Tomoshige S., Ishikawa M., Sato S.*, Switching of Photocatalytic Tyrosine/Histidine Labeling and Application to Photocatalytic Proximity Labeling. Int. J. Mol. Sci.23, 11622 (2022).
(52) Hughes A, M.*, Goldfinger J. A., Palmieri M. A., Ramos P., Santa Cruz I. S., Leo L. D., Garabalino M. A., Thorp S. I., Curotto P., Pozzi E. C. C., Kawai K., Sato S., Itoiz M. E., Trivillin V. A., Guidobono J. S., Nakamura H., Schwint A. E., Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-functionalized Closo-dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and in vivo bnct in the Hamster Cheek Pouch Oral Cancer Model. Life 12, 1082
(51) Nakane K.., Niwa T., Tsushima M., Tomoshige S., Taguchi H., Nakamura H., Ishikawa M., Sato S., BODIPY Catalyzes Proximity-Dependent Histidine Labelling. ChemCatChem 14, e202200077 (2022).
2021年度
(50) Hirai K., Yamashita H., Tomoshige S., Mishima Y., Niwa T., Ohgane K., Ishii M., Kanamitsu K., , Ikemi Y., Nakagawa S., Taguchi H., Sato S., Hashimoto Y., Ishikawa M., Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties, ACS Med. Chem. Lett. 13, 396–402 (2022)
(49) Tsushima M., Sato S., Miura K., Niwa T., Taguchi H., Nakamura H., Intracellular photocatalytic-proximity labeling for profiling protein-protein interactions in microenvironments. Chem. Commun. 58, 1926–1929 (2022)
(48) Sato S., Matsumura M., Ueda H., Nakamura H., Preparation of antigen-responsive fluorogenic immunosensor by tyrosine chemical modification of antibody complementarity determining region. Chem. Commun. 57, 9760–9763 (2021)
(47) Tokuhiro T., Ishikawa A., Sato H., Takita S., Yoshikawa A., Anzai R., Sato S., Aoyagi R., Arita M., Aratani Y., Shimizu S., Tanaka M., Yotsumoto S., Oxidized phospholipids and neutrophil elastase coordinately play critical roles in NET formation. Front. Cell Dev. Biol. https://doi.org/10.3389/fcell.2021.718586
(46) Obara S., Nakane K., Fujimura C., Tomoshige S., Ishikawa M., Sato S., Functionalization of Human Serum Albumin by Tyrosine Click, Inter. J. Mol. Sci.22, 8676 (2021)
(45) Nakane K., Sato S., Niwa T., Tsushima M., Tomoshige S., Taguchi H., Ishikawa M., Nakamura H., Proximity Histidine Labeling by Umpolung Strategy Using Singlet Oxygen. J. Am. Chem. Soc. 143, 20, 7726–773. (2021) (supplementary cover、東北大プレスリリース、海外プレスリリース）
2020年度
(44) Kawai K., Nishimura K, Okada S., Sato S., Suzuki M., Takata T., Nakamura H., Cyclic RGD-Functionalized closo-Dodecaborate Albumin Conjugates as Integrin Targeting Boron Carriers for Neutron Capture Therapy. Mol. Pharm. 17, 3740–3747 (2020)
(43) Masuzawa T., Sato S., Niwa T., Taguchi H., Nakamura H., Oyoshi T., G-Quadruplex-Proximity Protein Labeling Based on Peroxidase Activity. Chem. Commun. 56, 11641–11644 (2020)3978 (2019)
(42) Sato S. , Nakamura H., Labeling of Peroxide-Induced Oxidative Stress Hotspots by Hemin-Catalyzed Tyrosine Click. Chem Pharm. Bull. 68, 885–890 (2020)
(41) Fuse S., Moriya W., Sato S., Nakamura H., Investigation into the influence of an acrylic acid acceptor in organic D-π-A sensitizers against phototoxicity. Bioorg. Med. Chem. 28, 115558 (2020)
(40) Sato S., Nakane K., Nakamura H., Laccase-Catalysed Tyrosine Click Reaction. Org. Biomol. Chem. 18, 3664-3668 (2020)
(39) Sato S., Matsumura M., Kadonosono T., Abe S., Ueno T., Ueda H., Nakamura H., Site-Selective Protein Chemical Modification of Exposed Tyrosine Residues Using Tyrosine Click Reaction. Bioconjugate Chem. 31, 1417–1424 (2020)
(38) Yimchuen W., Kadonosono T., Ota Y., Sato S., Kitazawa M., Shiozawa T., Kuchimaru T., Taki M., Ito Y., Nakamura H., Kizaka-Kondoh S., Strategic design to create HER2-targeting proteins with target-binding peptides immobilized on a fibronectin type III domain scaffold. RSC Advances, 10, 15154-15162 (2020)
2019年度以前
(37) Kikuchi S., Sato S., Nakamura H., Carrier Protein-Based Boron Delivery to Tumor. Appl. Radiat. Isot. 157, 109011 (2020)
(36) Fuse F., Suzuki K., Kuchimaru T., Kadonosono T., Ueda H., Sato S., Kizaka-Kondoh S., Nakamura H., Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity. Bioorg. Med. Chem. 28, 115207 (2020)
(35) Tsushima M., Sato S., Niwa T., Taguchi H., Nakamura H., Catalyst-Proximity Protein Chemical Labelling on Affinity Beads Targeting Endogenous Lectins. Chem. Commun. 55, 13275-13278 (2019)
(34) Asai T., Liu H., Ozeki, Y., Sato S., Hayashi T., Nakamura H., Imaging of cellular uptake of boron cluster compound by stimulated Raman scattering microscopy. Appl. Phys. Express 12, 112004 (2019)
(33) Mochizuki M., Sato S., Asatyas S., Leśnikowski Z. J., Hayashi T., Nakamura H., Raman cell imaging with boron cluster molecules conjugated with biomolecules. RSC Advances. 9, 23973-23978 (2019)
(32) Ishii S., Sato S., Asami H., Hasegawa T., Kohno J., Nakamura H., Design of S-S Bond Containing Maleimide-Conjugated closo-Dodecaborate (SSMID): Identification of Its Unique Modification Sites on Albumin and Investigation of Intracellular Uptake. Org. Biomol. Chem. 17, 5496-5499 (2019)（cover picture）
(31) Sato S., Yoshida M., Hatano K., Matsumura M., Nakamura H. N’-acyl-N-methylphenylenediamine as a novel proximity labeling agent for signal amplification in immunohistochemistry. Bioorg. Med. Chem. 27, 1110-1118 (2019)
(30) Fuse S., Takizawa M., Sato S., Okazaki, S., Nakamura H. Elucidating the mode of action for thiophene-based organic D-π-A sensitizers for use in photodynamic therapy. Bioorg. Med. Chem. 27, 315-321 (2019).
(29) Fuentes I., García-Mendiola T., Sato S., Pita M., Nakamura H., Lorenzo E., Teixidor, F. Marques F., Viñas C. Metallacarboranes on the road to anticancer therapies: cellular uptake, DNA interaction and biological evaluation of cobaltabisdicarbollide ([COSAN]–). Chem. Eur. J. 24, 17239-17254 (2018).（Front Cover Picture）
(28) Fuse S., Matsumura K., Takizawa M., Sato S., Nakamura H. The design, synthesis, and evaluation of organic dithienopyrrole-based D-π-A dyes for use as sensitizers in photodynamic therapy. Bioorg. Med. Chem. Lett. 28, 3099-3104 (2018).
(27) Sato S., Hatano K., Tsushima M., Nakamura H. 1-Methyl-4-aryl-urazole (MAUra) Labels Tyrosine in Proximity to Ruthenium Photocatalyst. Chem. Commun. 54, 5871-5874 (2018)
(26) Nakamura H., Kikuchi H., Kawai K., Ishii S., Sato S. closo-Dodecaborate-conjugated human serum albumins: preparation and in vivo selective boron delivery to tumor. Pure Appl. Chem., 90, 745-753 (2018)
(25) Fuse S., Inaba M., Sato S., Joshi M., Nakamura H., Synthesis of Pyrazolofuropyrazine via One-pot SNAr Reaction/Intramolecular C-H Direct Arylation. Synthesis, 50, 1493-1498 (2018).
(24) Fuse S., Takizawa M., Matsumura K., Sato S., Okazaki S., Nakamura H., Thiophene-based, Organic D-π-A dyes as Potent Sensitizers for Photodynamic Therapy. Eur J. Org. Chem. 34, 5170-5177 (2017).
(23) Sato S., Ishii S., Nakamura H., Development of Albumin-closo-Dodecaborate Conjugates as Boron Carriers for Neutron Capture Therapy by Ru(bpy)3-Photocatalyzed Tyrosine Modification. Eur. J. Inorg. Chem. 4406-4410 (2017).（very important paper, cover picture）
(22) Tsushima M., Sato S., Nakamura H., Selective purification and chemical labeling of a target protein on ruthenium photocatalyst-functionalized affinity beads. Chem. Commun. 53, 4838-4841 (2017)
(21) Sato S., Nakamura K., Nakamura H., Horseradish-Peroxidase-Catalyzed Tyrosine Click Reaction. ChemBioChem. 18, 475–478 (2017).（inside cover picture）
(20) Fuse S., Ohuchi T., Asawa Y., Sato S., Nakamura H., Development of 1-Aryl-3-furanyl/Thienyl-imidazopyridine Templates for Inhibitors against Hypoxia Inducible Factor (HIF)-1 Transcriptional Activity, Bioorg. Med. Chem. Lett. 26, 5887–5890 (2016).
(19) Kikuchi S., Kanoh D., Sato S., Sakurai Y., Suzuki M., Nakamura H., Maleimide-Functionalized closo-Dodecaborate Albumin Conjugates (MID-AC): The Unique Ligation at both Cysteine and Lysine Residues Enabling to Efficient Boron Delivery to Tumor for Neutron Capture Therapy J. Control. Release 237, 160–167 (2016).
(18) Tachikawa S., Sato S., Hazama H., Kaneda Y., Awazu K., Nakamura H., Localization-Dependent Cell-Killing Effects of Protoporphyrin (PPIX)-Lipid Micelles and Liposomes in Photodynamic Therapy. Bioorg. Med. Chem. 23, 7578-7584 (2015).
(17) Sato S., Nakamura K., Nakamura H., Tyrosine-Specific Chemical Modification with in situ Hemin-Activated Luminol Derivatives. ACS Chem. Biol. 10, 2633-2640. (2015).
(16) Li G., Azuma S., Sato S., Minegishi H., Nakamura H., ortho-Carboranylphenoxyacetanilides as Inhibitors of Hypoxia-Inducible Factor (HIF)-1Transcriptional Activity and Heat Shock Protein (HSP) 60 Chaperon Activity. Bioorg. Med. Chem. Lett. 25, 2624-2628 (2015).
(15) Sato S., Morita K., Nakamura H., Regulation of target protein knockdown and labeling using ligand-directed Ru(bpy)3 photocatalyst. Bioconjugate Chem. 26, 250-256 (2015).
(14) Nakamura H., Tazaki L., Kanoh D., Sato S., Diaryl-substituted carboranes as inhibitors of hypoxia inducible factor-1 transcriptional activity. Pure Appl. Chem.87(2),145-154 (2015).
(13) Tachikawa S., El-Zaria M. E., Inomata R., Sato S., Nakamura H., Synthesis of protoporphyrin-lipids and biological evaluation of micelles and liposomes. Bioorg. Med. Chem. 22, 4745－4751 (2014).
(12) Nakamura H., Ban H. S., Shimizu K.., Minegishi H., Sato S. Design of Photoaffinity Probe Molecules for Identification and Modification of Target Proteins. J. Photopolym. Sci. Technol. 27, 453-458 (2014).
(11) Nakamura H., Tazaki L., Kanoh D., Sato S., Ban H. S., Diaryl-substituted ortho-carboranes as a new class of hypoxia inducible factor-1α inhibitors, Dalton Trans 43, 4941-4944 (2014).
(10) Sato S. Nakamura H. Ligand-directed Selective Protein Modification Based on Local Single Electron Transfer Catalysis. Angew. Chem. Int. Ed. 52, 8681-8684 (2013).
(9) Sato S., Inokuma T., Otsubo N., Burton D. R., Barbas C. F. III. Chemically Programmed Antibodies As HIV-1 Attachment Inhibitors. ACS Med. Chem. Lett. 4, 460-465 (2013).
(8) Nakamura H., Yasui Y., Maruyama M., Minegishi H., Ban H. S., Sato S., Development of Hypoxia-Inducible Factor (HIF)-1α Inhibitors: Effect of ortho-Carborane Substituents on HIF Transcriptional -Activity under Hypoxia. Bioorg. Med. Chem. Lett. 23, 806-810 (2013).
(7) Takeuchi A., Hori M., Sato S., Ban H. S., Kuchimaru T., Kizaka-Kondoh S., Yamori T., Nakamura H. Synthesis and biological evaluation of furylindazoles as hypoxia inducible factor (HIF)-1α inhibitors. Med. Chem. Commun. 3, 1455-1461 (2012).
(6) Murasawa S., Iuchi K., Sato S., Noguchi-Yachide T., Sodeoka M., Yokomatsu T., Dodo K., Hashimoto Y., Aoyama H. Small-molecular inhibitors of Ca2+-induced mitochondrial permeability transition (MPT) derived from muscle relaxant dantrolene. Bioorg. Med. Chem., 20, 6384-6393, (2012).
(5) Itoh, Y., Ishikawa, M., Kitaguchi R., Sato, S., Naito, M. and Hashimoto, Y. Development of target protein-selective degradation inducer for protein knockdown. Bioorg. Med. Chem., 19, 3229-3241, (2011).
(4) Aoyama, H., Sako, K., Sato, S., Nakamura, M., Miyachi, H., Goto, Y., Okamoto, M., Baba, M. and Hashimoto, Y. Polymethylated γ-Carbolines with Potent Anti-bovine Viral Diarrhea Virus (BVDV) Activity. Heterocycles, 77, 779-785, (2009).
(3) Sato, S., Tetsuhashi, M., Sekine, K., Miyachi, H., Naito, M., Hashimoto, Y. and Aoyama, H. Degradation-promoters of cellular inhibitor of apoptosis protein 1 based on bestatin and Actinonin. Bioorg. Med. Chem., 16, 4685-4698, (2008).
(2)Sako, K., Aoyama, H., Sato, S., Hashimoto, Y. and Baba, M. γ-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity. Bioorg. Med. Chem., 16, 3780-3790, (2008).
(1) Sato, S., Aoyama, H., Miyachi, H., Naito, M. and Hashimoto, Y. Demonstration of direct binding of cIAP1 degradation-promoting bestatin analogs to BIR3 domain: synthesis and application of fluorescent bestatin ester analogs. Bioorg. Med. Chem. Lett., 18, 3354-3358, (2008).